Design of siRNA Therapeutics from the Molecular Scale

Design of siRNA Therapeutics from the Molecular Scale

While protein-based therapeutics is well-established in the market, development of nucleic acid therapeutics has lagged. Short interfering RNAs (siRNAs) represent an exciting new direction for the pharmaceutical industry. These small, chemically synthesized RNAs can knock down the expression of targ...

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Bibliographic Details
Main Authors: Christina Chan, S. Patrick Walton, Daniel Vocelle, Phillip Angart
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:Pharmaceuticals
Subjects:
siRNA therapeutic
RNAi
liver cancer
siRNA design
delivery vehicle design
Online Access:http://www.mdpi.com/1424-8247/6/4/440

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