Cardiovascular risk assessment in the resource limited setting of Western Honduras: An epidemiological perspective

• Main Authors: Eleazar Enrique Montalvan Sanchez, Samuel Alejandro Urrutia, Aida Argentina Rodriguez, Gabriela Duarte, Axel Murillo, Ricardo Rivera, Andrea Alejandra Paredes Henriquez, Daniela Maria Montalvan Sanchez, Eva Ordoñez, Dalton Argean Norwood, Lucia Belem Dominguez, Ricardo Leonel Dominguez, Karla Torres, Esmelia Michell Reyes Fajardo, Carlos Amilcar Godoy
• Format: Article
• Language: English
• Published: Elsevier 2020-04-01
• Series: International Journal of Cardiology: Heart & Vasculature
• Online Access: http://www.sciencedirect.com/science/article/pii/S235290671930257X

Cardiovascular Disease (CVD) epidemiology varies significantly among Low and Middle-Income Countries. Honduras is the Central American country with the highest Ischemic Heart Disease and CVD mortality rates. The aim of this study was to assess the individual CVD risk factors and calculate Cardiovascular Risk Assessment Scores (CVRAS) from the population. Methods: A cross-sectional study in western Honduras. Estimation of CV risk was performed using Framingham, MESA, ACC/AHA-PCEs and ESC SCORE calculators. Results: 38% were male. For men and women respectively; 49% and 48% had self-reported hypertension (HTN), on measured blood pressure only 18% and 30% had normal readings. Diabetes Mellitus was reported in 19% and 22%. Tobacco use was 14% and 3%. Self-reported regular exercise was 39.9% and 25%. Obesity was diagnosed in 24% and 24%. Lipid profile; total cholesterol was ≥200 mg/dl in 63% of subjects. LDL-C was elevated (>100 mg/dl) in 74% of participants, 9% had LDL-C levels higher than 190 mg/dl. Triglycerides were high (>160 mg/dl) in 60%, of these subjects 22% were taking lipid-lowering medications. 52% reported family-history of CVD. The risk calculation for men and women respectively for each CVRAS were; AHA/ACC-PCEs high risk (score ≥ 7.5%) in 62% and 30%, FRS high risk (score ≥ 20%) 46% and 15%, MESA high risk (Score ≥ 7.5%) in 70.6% and 17.7%, ESC SCORE high risk (score ≥ 5% in 32.4% and 11.8%). Conclusions: CV risk calculations revealed higher than rates than expected with consequently reflected on higher than estimated CVRAS. This represents the first report of its kind in Honduras. Keywords: Risk factors, Body mass index, Cardiovascular diseases, Cholesterol