Patient-specific iPSC-derived cellular models of LGMDR1

Patient-specific iPSC-derived cellular models of LGMDR1

Limb-girdle muscular dystrophy recessive 1 (LGMDR1) represents one of the most common types of LGMD in the population, where patients develop a progressive muscle degeneration. The disease is caused by mutations in calpain 3 gene, with over 500 mutations reported to date. However, the molecular even...

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Bibliographic Details
Main Authors: A.J. Mateos-Aierdi, M. Dehesa-Etxebeste, M. Goicoechea, A. Aiastui, Y. Richaud-Patin, S. Jiménez-Delgado, A. Raya, N. Naldaiz-Gastesi, A. López de Munain
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Stem Cell Research
Subjects:
Induced pluripotent stem cells
LGMDR1
CAPN3
Skeletal muscle
Dystrophin
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506121001793

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http://www.sciencedirect.com/science/article/pii/S1873506121001793

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