Morphologic and Molecular Characterization of Adrenals and Adrenal Rest Affected by Congenital Adrenal Hyperplasia

Morphologic and Molecular Characterization of Adrenals and Adrenal Rest Affected by Congenital Adrenal Hyperplasia

IntroductionAdrenocortical hyperplasia and adrenal rest tumor (ART) formation are common in congenital adrenal hyperplasia (CAH). Although driven by excessive corticotropin, much is unknown regarding the morphology and transformation of these tissues. Our study objective was to characterize CAH-affe...

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Bibliographic Details
Main Authors: Vipula Kolli, Isabela Werneck da Cunha, SunA Kim, James R. Iben, Ashwini Mallappa, Tianwei Li, Alison Gaynor, Steven L. Coon, Martha M. Quezado, Deborah P. Merke
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Endocrinology
Subjects:
adrenal insufficiency
congenital adrenal hyperplasia
testicular adrenal rest tissue
para-ovarian adrenal rest tissue
principal component analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.730947/full

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