Flavonoids from Symplocos racemosa

A novel isoflavone glycoside, peseudobatigenin 7-O-[β-d-apiofuranosyl-(1''''→5''')-O-β-d-apiofuranosyl-(1'''→6'')]-β-d-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known...

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Main Authors: Mila Jung, Janggyoo Choi, Hee-Sung Chae, Jae Youl Cho, Young-Dong Kim, Khin Myo Htwe, Woo-Shin Lee, Young-Won Chin, Jinwoong Kim, Kee Dong Yoon
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/1/358
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spelling doaj-67deab68f5c54bff9e564970d7e0162f2020-11-25T00:48:56ZengMDPI AGMolecules1420-30492014-12-0120135836510.3390/molecules20010358molecules20010358Flavonoids from Symplocos racemosaMila Jung0Janggyoo Choi1Hee-Sung Chae2Jae Youl Cho3Young-Dong Kim4Khin Myo Htwe5Woo-Shin Lee6Young-Won Chin7Jinwoong Kim8Kee Dong Yoon9College of Pharmacy, The Catholic University of Korea, Bucheon 420-743, KoreaCollege of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Seoul 151-742, KoreaCollege of Pharmacy and RFIND-BKplus Team, Dongguk University-Seoul, 32 Dongguk-lo, Ilsan dong-gu, Goyang, Gyeonggi-do 410-820, KoreaDepartment of Genetic Engineering, Sungkyunkwan University, Suwon 440-746, KoreaDepartment of Life Science, Hallym University, Chuncheon 200-702, KoreaPopa Mountain Park, Forest Department, Kyaukpadaung Township, Mandalay Division, MyanmarDepartment of Forest Sciences, Seoul National University, Seoul 151-921, KoreaCollege of Pharmacy and RFIND-BKplus Team, Dongguk University-Seoul, 32 Dongguk-lo, Ilsan dong-gu, Goyang, Gyeonggi-do 410-820, KoreaCollege of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Seoul 151-742, KoreaCollege of Pharmacy, The Catholic University of Korea, Bucheon 420-743, KoreaA novel isoflavone glycoside, peseudobatigenin 7-O-[β-d-apiofuranosyl-(1''''→5''')-O-β-d-apiofuranosyl-(1'''→6'')]-β-d-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known flavonoids (2–16). Their structures were characterized by Q-TOF mass, optical rotation, UV, 1D and 2D-NMR spectroscopic data. Compounds 3, 9, 16 showed moderate inhibitory activities against NO production with IC50 value of 88.2, 42.1 and 74.3 μM, respectively.http://www.mdpi.com/1420-3049/20/1/358flavonoidssympracemosideSymplocos racemosa
collection DOAJ
language English
format Article
sources DOAJ
author Mila Jung
Janggyoo Choi
Hee-Sung Chae
Jae Youl Cho
Young-Dong Kim
Khin Myo Htwe
Woo-Shin Lee
Young-Won Chin
Jinwoong Kim
Kee Dong Yoon
spellingShingle Mila Jung
Janggyoo Choi
Hee-Sung Chae
Jae Youl Cho
Young-Dong Kim
Khin Myo Htwe
Woo-Shin Lee
Young-Won Chin
Jinwoong Kim
Kee Dong Yoon
Flavonoids from Symplocos racemosa
Molecules
flavonoids
sympracemoside
Symplocos racemosa
author_facet Mila Jung
Janggyoo Choi
Hee-Sung Chae
Jae Youl Cho
Young-Dong Kim
Khin Myo Htwe
Woo-Shin Lee
Young-Won Chin
Jinwoong Kim
Kee Dong Yoon
author_sort Mila Jung
title Flavonoids from Symplocos racemosa
title_short Flavonoids from Symplocos racemosa
title_full Flavonoids from Symplocos racemosa
title_fullStr Flavonoids from Symplocos racemosa
title_full_unstemmed Flavonoids from Symplocos racemosa
title_sort flavonoids from symplocos racemosa
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2014-12-01
description A novel isoflavone glycoside, peseudobatigenin 7-O-[β-d-apiofuranosyl-(1''''→5''')-O-β-d-apiofuranosyl-(1'''→6'')]-β-d-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known flavonoids (2–16). Their structures were characterized by Q-TOF mass, optical rotation, UV, 1D and 2D-NMR spectroscopic data. Compounds 3, 9, 16 showed moderate inhibitory activities against NO production with IC50 value of 88.2, 42.1 and 74.3 μM, respectively.
topic flavonoids
sympracemoside
Symplocos racemosa
url http://www.mdpi.com/1420-3049/20/1/358
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AT jaeyoulcho flavonoidsfromsymplocosracemosa
AT youngdongkim flavonoidsfromsymplocosracemosa
AT khinmyohtwe flavonoidsfromsymplocosracemosa
AT wooshinlee flavonoidsfromsymplocosracemosa
AT youngwonchin flavonoidsfromsymplocosracemosa
AT jinwoongkim flavonoidsfromsymplocosracemosa
AT keedongyoon flavonoidsfromsymplocosracemosa
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