Flavonoids from Symplocos racemosa
A novel isoflavone glycoside, peseudobatigenin 7-O-[β-d-apiofuranosyl-(1''''→5''')-O-β-d-apiofuranosyl-(1'''→6'')]-β-d-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-12-01
|
Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/20/1/358 |
id |
doaj-67deab68f5c54bff9e564970d7e0162f |
---|---|
record_format |
Article |
spelling |
doaj-67deab68f5c54bff9e564970d7e0162f2020-11-25T00:48:56ZengMDPI AGMolecules1420-30492014-12-0120135836510.3390/molecules20010358molecules20010358Flavonoids from Symplocos racemosaMila Jung0Janggyoo Choi1Hee-Sung Chae2Jae Youl Cho3Young-Dong Kim4Khin Myo Htwe5Woo-Shin Lee6Young-Won Chin7Jinwoong Kim8Kee Dong Yoon9College of Pharmacy, The Catholic University of Korea, Bucheon 420-743, KoreaCollege of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Seoul 151-742, KoreaCollege of Pharmacy and RFIND-BKplus Team, Dongguk University-Seoul, 32 Dongguk-lo, Ilsan dong-gu, Goyang, Gyeonggi-do 410-820, KoreaDepartment of Genetic Engineering, Sungkyunkwan University, Suwon 440-746, KoreaDepartment of Life Science, Hallym University, Chuncheon 200-702, KoreaPopa Mountain Park, Forest Department, Kyaukpadaung Township, Mandalay Division, MyanmarDepartment of Forest Sciences, Seoul National University, Seoul 151-921, KoreaCollege of Pharmacy and RFIND-BKplus Team, Dongguk University-Seoul, 32 Dongguk-lo, Ilsan dong-gu, Goyang, Gyeonggi-do 410-820, KoreaCollege of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Seoul 151-742, KoreaCollege of Pharmacy, The Catholic University of Korea, Bucheon 420-743, KoreaA novel isoflavone glycoside, peseudobatigenin 7-O-[β-d-apiofuranosyl-(1''''→5''')-O-β-d-apiofuranosyl-(1'''→6'')]-β-d-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known flavonoids (2–16). Their structures were characterized by Q-TOF mass, optical rotation, UV, 1D and 2D-NMR spectroscopic data. Compounds 3, 9, 16 showed moderate inhibitory activities against NO production with IC50 value of 88.2, 42.1 and 74.3 μM, respectively.http://www.mdpi.com/1420-3049/20/1/358flavonoidssympracemosideSymplocos racemosa |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mila Jung Janggyoo Choi Hee-Sung Chae Jae Youl Cho Young-Dong Kim Khin Myo Htwe Woo-Shin Lee Young-Won Chin Jinwoong Kim Kee Dong Yoon |
spellingShingle |
Mila Jung Janggyoo Choi Hee-Sung Chae Jae Youl Cho Young-Dong Kim Khin Myo Htwe Woo-Shin Lee Young-Won Chin Jinwoong Kim Kee Dong Yoon Flavonoids from Symplocos racemosa Molecules flavonoids sympracemoside Symplocos racemosa |
author_facet |
Mila Jung Janggyoo Choi Hee-Sung Chae Jae Youl Cho Young-Dong Kim Khin Myo Htwe Woo-Shin Lee Young-Won Chin Jinwoong Kim Kee Dong Yoon |
author_sort |
Mila Jung |
title |
Flavonoids from Symplocos racemosa |
title_short |
Flavonoids from Symplocos racemosa |
title_full |
Flavonoids from Symplocos racemosa |
title_fullStr |
Flavonoids from Symplocos racemosa |
title_full_unstemmed |
Flavonoids from Symplocos racemosa |
title_sort |
flavonoids from symplocos racemosa |
publisher |
MDPI AG |
series |
Molecules |
issn |
1420-3049 |
publishDate |
2014-12-01 |
description |
A novel isoflavone glycoside, peseudobatigenin 7-O-[β-d-apiofuranosyl-(1''''→5''')-O-β-d-apiofuranosyl-(1'''→6'')]-β-d-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known flavonoids (2–16). Their structures were characterized by Q-TOF mass, optical rotation, UV, 1D and 2D-NMR spectroscopic data. Compounds 3, 9, 16 showed moderate inhibitory activities against NO production with IC50 value of 88.2, 42.1 and 74.3 μM, respectively. |
topic |
flavonoids sympracemoside Symplocos racemosa |
url |
http://www.mdpi.com/1420-3049/20/1/358 |
work_keys_str_mv |
AT milajung flavonoidsfromsymplocosracemosa AT janggyoochoi flavonoidsfromsymplocosracemosa AT heesungchae flavonoidsfromsymplocosracemosa AT jaeyoulcho flavonoidsfromsymplocosracemosa AT youngdongkim flavonoidsfromsymplocosracemosa AT khinmyohtwe flavonoidsfromsymplocosracemosa AT wooshinlee flavonoidsfromsymplocosracemosa AT youngwonchin flavonoidsfromsymplocosracemosa AT jinwoongkim flavonoidsfromsymplocosracemosa AT keedongyoon flavonoidsfromsymplocosracemosa |
_version_ |
1725254063697690624 |