Interferon alpha induces establishment of alphaherpesvirus latency in sensory neurons in vitro.

Interferon alpha induces establishment of alphaherpesvirus latency in sensory neurons in vitro.

Several alphaherpesviruses, including herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV), establish lifelong latency in neurons of the trigeminal ganglion (TG). Although it is thought that efficient establishment of alphaherpesvirus latency is based on a subtle interplay between virus, neur...

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Bibliographic Details
Main Authors: Nick De Regge, Nina Van Opdenbosch, Hans J Nauwynck, Stacey Efstathiou, Herman W Favoreel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2947521?pdf=render

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