Combined GSTM1 and GSTT1 null genotypes are strong risk factors for atherogenesis in a Serbian population

Combined GSTM1 and GSTT1 null genotypes are strong risk factors for atherogenesis in a Serbian population

Abstract Oxidative stress (OS) plays an important role in atherogenesis and since glutathione S-transferases (GSTs) provide protection against OS, we have tested the hypothesis that deletion polymorphisms in two GSTs (GSTM1 and GSTT1) may affect the risk of developing atherosclerosis. A total of 382...

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Bibliographic Details
Main Authors: Ivana Grubisa, Petar Otasevic, Nada Vucinic, Biljana Milicic, Tanja Jozic, Slobodan Krstic, Jelena Milasin
Format: Article
Language:English
Published: Sociedade Brasileira de Genética
Series:Genetics and Molecular Biology
Subjects:
atherosclerosis
gene polymorphisms
glutathione S-transferases
oxidative stress
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018000100035&lng=en&tlng=en

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