Pioglitazone ameliorates neuronal damage after traumatic brain injury via the PPARγ/NF-κB/IL-6 signaling pathway

Pioglitazone ameliorates neuronal damage after traumatic brain injury via the PPARγ/NF-κB/IL-6 signaling pathway

Traumatic brain injury (TBI) is the major cause of high mortality and disability rates worldwide. Pioglitazone is an activator of peroxisome proliferator-activated receptor-gamma (PPARγ) that can reduce inflammation following TBI. Clinically, neuroinflammation after TBI lacks effective treatment. Al...

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Bibliographic Details
Main Authors: Yongbing Deng, Xue Jiang, Xiaoyan Deng, Hong Chen, Jie Xu, Zhaosi Zhang, Geli Liu, Zhu Yong, Chengfu Yuan, Xiaochuan Sun, Changdong Wang
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Genes and Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304219300339

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