The Presence of Precursors of Benign Pre-B Lymphoblasts (Hematogones) in the Bone Marrow of a Paediatric Patient with Cytomegalovirus Infection

The Presence of Precursors of Benign Pre-B Lymphoblasts (Hematogones) in the Bone Marrow of a Paediatric Patient with Cytomegalovirus Infection

Hematogones are normal B-lymphoid precursors that multiply in the bone marrow of small children and of adults with ferropenic anaemia, neuroblastoma or idiopathic thrombocytopenic purpura. They are not normally found in peripheral blood, and the immunophenotype is virtually indistinguishable from th...

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Main Authors: F Moreno-Madrid, J Uberos, M Díaz-Molina, A Ramírez-Arredondo, P Jiménez-Gámiz, A Molina-Carballo
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Clinical Medicine Insights: Oncology
Online Access:https://doi.org/10.4137/CMO.S751
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spelling doaj-67c81d16e95f4c58a769d68ae28ad5e62020-11-25T03:18:05ZengSAGE PublishingClinical Medicine Insights: Oncology1179-55492008-01-01210.4137/CMO.S751The Presence of Precursors of Benign Pre-B Lymphoblasts (Hematogones) in the Bone Marrow of a Paediatric Patient with Cytomegalovirus InfectionF Moreno-Madrid0J Uberos1M Díaz-Molina2A Ramírez-Arredondo3P Jiménez-Gámiz4A Molina-Carballo5Servicio de Pediatría; Ciudad Sanitaria Virgen de las Nieves. Granada (Spain).Distrito Sanitario Granada. (Spain).Servicio de Pediatría; Ciudad Sanitaria Virgen de las Nieves. Granada (Spain).Servicio de Pediatría; Ciudad Sanitaria Virgen de las Nieves. Granada (Spain).Servicio de Hematología; Ciudad Sanitaria Virgen de las Nieves. Granada (Spain).Distrito Sanitario Granada. (Spain).Hematogones are normal B-lymphoid precursors that multiply in the bone marrow of small children and of adults with ferropenic anaemia, neuroblastoma or idiopathic thrombocytopenic purpura. They are not normally found in peripheral blood, and the immunophenotype is virtually indistinguishable from that of B lymphoblasts. We discuss the case of a 3-month infant with an active cytomegalovirus infection, with hepatitis and pancytopenia associated with 13% hematogones in the bone marrow.https://doi.org/10.4137/CMO.S751
collection DOAJ
language English
format Article
sources DOAJ
author F Moreno-Madrid
J Uberos
M Díaz-Molina
A Ramírez-Arredondo
P Jiménez-Gámiz
A Molina-Carballo
spellingShingle F Moreno-Madrid
J Uberos
M Díaz-Molina
A Ramírez-Arredondo
P Jiménez-Gámiz
A Molina-Carballo
The Presence of Precursors of Benign Pre-B Lymphoblasts (Hematogones) in the Bone Marrow of a Paediatric Patient with Cytomegalovirus Infection
Clinical Medicine Insights: Oncology
author_facet F Moreno-Madrid
J Uberos
M Díaz-Molina
A Ramírez-Arredondo
P Jiménez-Gámiz
A Molina-Carballo
author_sort F Moreno-Madrid
title The Presence of Precursors of Benign Pre-B Lymphoblasts (Hematogones) in the Bone Marrow of a Paediatric Patient with Cytomegalovirus Infection
title_short The Presence of Precursors of Benign Pre-B Lymphoblasts (Hematogones) in the Bone Marrow of a Paediatric Patient with Cytomegalovirus Infection
title_full The Presence of Precursors of Benign Pre-B Lymphoblasts (Hematogones) in the Bone Marrow of a Paediatric Patient with Cytomegalovirus Infection
title_fullStr The Presence of Precursors of Benign Pre-B Lymphoblasts (Hematogones) in the Bone Marrow of a Paediatric Patient with Cytomegalovirus Infection
title_full_unstemmed The Presence of Precursors of Benign Pre-B Lymphoblasts (Hematogones) in the Bone Marrow of a Paediatric Patient with Cytomegalovirus Infection
title_sort presence of precursors of benign pre-b lymphoblasts (hematogones) in the bone marrow of a paediatric patient with cytomegalovirus infection
publisher SAGE Publishing
series Clinical Medicine Insights: Oncology
issn 1179-5549
publishDate 2008-01-01
description Hematogones are normal B-lymphoid precursors that multiply in the bone marrow of small children and of adults with ferropenic anaemia, neuroblastoma or idiopathic thrombocytopenic purpura. They are not normally found in peripheral blood, and the immunophenotype is virtually indistinguishable from that of B lymphoblasts. We discuss the case of a 3-month infant with an active cytomegalovirus infection, with hepatitis and pancytopenia associated with 13% hematogones in the bone marrow.
url https://doi.org/10.4137/CMO.S751
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