The role of TLR4 896 A>G and 1196 C>T in susceptibility to infections: a review and meta-analysis of genetic association studies.

BACKGROUND: Toll-like receptor 4 plays a role in pathogen recognition, and common polymorphisms may alter host susceptibility to infectious diseases. PURPOSE: To review the association of two common polymorphisms (TLR4 896A>G and TLR4 1196C>T) with infectious diseases. DATA SOURCES: We searche...

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Bibliographic Details
Main Authors: Panayiotis D Ziakas, Michael L Prodromou, Joseph El Khoury, Elias Zintzaras, Eleftherios Mylonakis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3840016?pdf=render