Monitoring Cell Death in Regorafenib-Treated Experimental Colon Carcinomas Using Annexin-Based Optical Fluorescence Imaging Validated by Perfusion MRI.

Monitoring Cell Death in Regorafenib-Treated Experimental Colon Carcinomas Using Annexin-Based Optical Fluorescence Imaging Validated by Perfusion MRI.

To investigate annexin-based optical fluorescence imaging (OI) for monitoring regorafenib-induced early cell death in experimental colon carcinomas in rats, validated by perfusion MRI and multiparametric immunohistochemistry.Subcutaneous human colon carcinomas (HT-29) in athymic rats (n = 16) were i...

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Bibliographic Details
Main Authors: Philipp M Kazmierczak, Egon Burian, Ralf Eschbach, Heidrun Hirner-Eppeneder, Matthias Moser, Lukas Havla, Michel Eisenblätter, Maximilian F Reiser, Konstantin Nikolaou, Clemens C Cyran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4578959?pdf=render

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http://europepmc.org/articles/PMC4578959?pdf=render

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