Skeletal muscle secreted factors prevent glucocorticoid-induced osteocyte apoptosis through activation of β-catenin
It is a widely held belief that the sole effect of muscle on bone is through mechanical loading. However, as the two tissues are intimately associated, we hypothesized that muscle myokines may have positive effects on bone. We found that factors produced by muscle will protect osteocytes from underg...
Main Authors: | K Jähn, N Lara-Castillo, L Brotto, CL Mo, ML Johnson, M Brotto, LF Bonewald |
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Format: | Article |
Language: | English |
Published: |
AO Research Institute Davos
2012-09-01
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Series: | European Cells & Materials |
Subjects: | |
Online Access: | http://www.ecmjournal.org/journal/papers/vol024/pdf/v024a14.pdf |
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