Myopic Laser-Assisted Subepithelial Keratectomy (LASEK) outcomes using three different excimer laser platforms: a retrospective observational study

Abstract Background To compare the visual and refractive outcomes after myopic LASEK using three different excimer lasers and standardized surgical and mitomycin C (MMC) application protocols. Methods In this retrospective, observational cohort study, we examined 122 eyes treated with Allegretto, 13...

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Main Authors: Isabel Rodríguez-Pérez, Juan Gros-Otero, Miguel A. Teus, Rafael Cañones, Montserrat García-González
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Ophthalmology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12886-019-1214-y
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spelling doaj-67ac586570d140758dc8e3bffb6e68912020-11-25T03:41:50ZengBMCBMC Ophthalmology1471-24152019-10-0119111210.1186/s12886-019-1214-yMyopic Laser-Assisted Subepithelial Keratectomy (LASEK) outcomes using three different excimer laser platforms: a retrospective observational studyIsabel Rodríguez-Pérez0Juan Gros-Otero1Miguel A. Teus2Rafael Cañones3Montserrat García-González4Clínica Novovisión MadridClínica RementeríaClínica Novovisión MadridHospital Universitario “Príncipe de Asturias”, University of Alcalá, Alcalá de HenaresClínica Novovisión MadridAbstract Background To compare the visual and refractive outcomes after myopic LASEK using three different excimer lasers and standardized surgical and mitomycin C (MMC) application protocols. Methods In this retrospective, observational cohort study, we examined 122 eyes treated with Allegretto, 135 eyes treated with Esiris and 137 eyes treated with Technolas excimer lasers. All eyes were treated under the same surgical protocol, and a standardized MMC dosage was used. The three groups were refraction-matched, and both visual and refractive outcomes were evaluated at 1 and 7 days and 1 and 3 months after surgery. Results At 3 months postsurgery, Allegretto provided significantly better outcomes than Esiris and Technolas in terms of postoperative uncorrected distance visual acuity (UDVA) (1.11 ± 0.2 vs 1.01 ± 0.2 vs 0.98 ± 0.2) (P = 0.0001), corrected distance visual acuity (CDVA) (1.13 ± 0.2 vs 1.10 ± 0.1 vs 1.04 ± 0.2) (P = 0.0001), residual sphere (− 0.01 ± 0.2 vs + 0.29 ± 0.7 vs + 0.27 ± 0.6) (P = 0.0001), and efficacy index (0.99 ± 0.2 vs 0.90 ± 0.2 vs 0.91 ± 0.2) (P = 0.0004). Conclusions We found slightly better visual and refractive outcomes in the Allegretto group at 3 months post-op after LASEK with MMC to correct myopia.http://link.springer.com/article/10.1186/s12886-019-1214-yMyopiaLASEKExcimer laserMitomycin C
collection DOAJ
language English
format Article
sources DOAJ
author Isabel Rodríguez-Pérez
Juan Gros-Otero
Miguel A. Teus
Rafael Cañones
Montserrat García-González
spellingShingle Isabel Rodríguez-Pérez
Juan Gros-Otero
Miguel A. Teus
Rafael Cañones
Montserrat García-González
Myopic Laser-Assisted Subepithelial Keratectomy (LASEK) outcomes using three different excimer laser platforms: a retrospective observational study
BMC Ophthalmology
Myopia
LASEK
Excimer laser
Mitomycin C
author_facet Isabel Rodríguez-Pérez
Juan Gros-Otero
Miguel A. Teus
Rafael Cañones
Montserrat García-González
author_sort Isabel Rodríguez-Pérez
title Myopic Laser-Assisted Subepithelial Keratectomy (LASEK) outcomes using three different excimer laser platforms: a retrospective observational study
title_short Myopic Laser-Assisted Subepithelial Keratectomy (LASEK) outcomes using three different excimer laser platforms: a retrospective observational study
title_full Myopic Laser-Assisted Subepithelial Keratectomy (LASEK) outcomes using three different excimer laser platforms: a retrospective observational study
title_fullStr Myopic Laser-Assisted Subepithelial Keratectomy (LASEK) outcomes using three different excimer laser platforms: a retrospective observational study
title_full_unstemmed Myopic Laser-Assisted Subepithelial Keratectomy (LASEK) outcomes using three different excimer laser platforms: a retrospective observational study
title_sort myopic laser-assisted subepithelial keratectomy (lasek) outcomes using three different excimer laser platforms: a retrospective observational study
publisher BMC
series BMC Ophthalmology
issn 1471-2415
publishDate 2019-10-01
description Abstract Background To compare the visual and refractive outcomes after myopic LASEK using three different excimer lasers and standardized surgical and mitomycin C (MMC) application protocols. Methods In this retrospective, observational cohort study, we examined 122 eyes treated with Allegretto, 135 eyes treated with Esiris and 137 eyes treated with Technolas excimer lasers. All eyes were treated under the same surgical protocol, and a standardized MMC dosage was used. The three groups were refraction-matched, and both visual and refractive outcomes were evaluated at 1 and 7 days and 1 and 3 months after surgery. Results At 3 months postsurgery, Allegretto provided significantly better outcomes than Esiris and Technolas in terms of postoperative uncorrected distance visual acuity (UDVA) (1.11 ± 0.2 vs 1.01 ± 0.2 vs 0.98 ± 0.2) (P = 0.0001), corrected distance visual acuity (CDVA) (1.13 ± 0.2 vs 1.10 ± 0.1 vs 1.04 ± 0.2) (P = 0.0001), residual sphere (− 0.01 ± 0.2 vs + 0.29 ± 0.7 vs + 0.27 ± 0.6) (P = 0.0001), and efficacy index (0.99 ± 0.2 vs 0.90 ± 0.2 vs 0.91 ± 0.2) (P = 0.0004). Conclusions We found slightly better visual and refractive outcomes in the Allegretto group at 3 months post-op after LASEK with MMC to correct myopia.
topic Myopia
LASEK
Excimer laser
Mitomycin C
url http://link.springer.com/article/10.1186/s12886-019-1214-y
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