Dynamic Reorganization of the Cytoskeleton during Apoptosis: The Two Coffins Hypothesis

Dynamic Reorganization of the Cytoskeleton during Apoptosis: The Two Coffins Hypothesis

During apoptosis, cells undergo characteristic morphological changes in which the cytoskeleton plays an active role. The cytoskeleton rearrangements have been mainly attributed to actinomyosin ring contraction, while microtubule and intermediate filaments are depolymerized at early stages of apoptos...

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Bibliographic Details
Main Authors: Suleva Povea-Cabello, Manuel Oropesa-Ávila, Patricia de la Cruz-Ojeda, Marina Villanueva-Paz, Mario de la Mata, Juan Miguel Suárez-Rivero, Mónica Álvarez-Córdoba, Irene Villalón-García, David Cotán, Patricia Ybot-González, José A. Sánchez-Alcázar
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:International Journal of Molecular Sciences
Subjects:
apoptosis
apoptotic microtubule network
microtubules
actin filaments
genotoxic drugs
Online Access:https://www.mdpi.com/1422-0067/18/11/2393

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