MicroRNA-143 modulates the expression of Natriuretic Peptide Receptor 3 in cardiac cells

Abstract Natriuretic Peptide Receptor 3 (NPR3), the clearance receptor for extracellular bio-active natriuretic peptides (NPs), plays important roles in the homeostasis of body fluid volume and vascular tone. Using luciferase reporter and antagomir-based silencing assays, we demonstrated that the ex...

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Bibliographic Details
Main Authors: Juan Wang, Kai Sing Tong, Lee Lee Wong, Oi-Wah Liew, Divya Raghuram, Arthur Mark Richards, Yei-Tsung Chen
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25489-3

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