Aberrant insulin signaling in Alzheimer’s disease: current knowledge

Aberrant insulin signaling in Alzheimer’s disease: current knowledge

Alzheimer’s disease (AD) is the most common form of dementia affecting elderly people. AD is a multifaceted pathology characterized by accumulation of extracellular neuritic plaques, intracellular neurofibrillary tangles (NFTs) and neuronal loss mainly in the cortex and hippocampus. AD etiology appe...

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Bibliographic Details
Main Authors:	Gaurav eBedse, Fabio eDi Domenico, Gaetano eServiddio, Tommaso eCassano
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-06-01
Series:	Frontiers in Neuroscience
Subjects:	Alzheimer’s disease beta amyloid insulin signaling Insulin-like growth factor phosphorylated tau
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00204/full

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