Effective computational detection of piRNAs using n-gram models and support vector machine

Effective computational detection of piRNAs using n-gram models and support vector machine

Abstract Background Piwi-interacting RNAs (piRNAs) are a new class of small non-coding RNAs that are known to be associated with RNA silencing. The piRNAs play an important role in protecting the genome from invasive transposons in the germline. Recent studies have shown that piRNAs are linked to th...

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Bibliographic Details
Main Authors: Chun-Chi Chen, Xiaoning Qian, Byung-Jun Yoon
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Bioinformatics
Subjects:
piwi-interacting RNA (piRNA)
piRNA prediction
n-gram model (NGM)
Support vector machine (SVM)
Online Access:http://link.springer.com/article/10.1186/s12859-017-1896-1

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