Recombinant E2 glycoprotein of bovine viral diarrhea virus induces a solid humoral neutralizing immune response but fails to confer total protection in cattle

Recombinant E2 glycoprotein of bovine viral diarrhea virus induces a solid humoral neutralizing immune response but fails to confer total protection in cattle

Two recombinant baculoviruses were produced in order to obtain a bovine viral diarrhea virus (BVDV) immunogen: AcNPV/E2 expressing E2 glycoprotein, and AcNPV/E0E1E2 expressing the polyprotein region coding for the three structural proteins of BVDV (E0, E1, and E2). Mice were immunized with Sf9 cells...

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Bibliographic Details
Main Authors:	S. Chimeno Zoth, M.R. Leunda, A. Odeón, O. Taboga
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2007-06-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Bovine viral diarrhea virus Recombinant E2 glycoprotein
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000600010

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