C-kit+ resident cardiac stem cells improve left ventricular fibrosis in pressure overload

C-kit+ resident cardiac stem cells improve left ventricular fibrosis in pressure overload

To investigate the effect of resident cardiac stem cells (RCSC) on myocardial remodeling, c-kit+ RCSC were isolated from hearts of C57Bl/6-Tg (ACTb-EGFP)1Osb/J mice expressing green fluorescent protein and expanded in vitro. C57/Bl6N wildtype mice were subjected to transverse aortic constriction (TA...

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Bibliographic Details
Main Authors: Andrey Kazakov, Timo Meier, Christian Werner, Rabea Hall, Birgit Klemmer, Christina Körbel, Frank Lammert, Christoph Maack, Michael Böhm, Ulrich Laufs
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Stem Cell Research
Subjects:
C-kit+
Cardiac stem cells
Fibrosis
Transplantation
Online Access:http://www.sciencedirect.com/science/article/pii/S187350611500152X

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http://www.sciencedirect.com/science/article/pii/S187350611500152X

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