Patients with Proliferative Lupus Nephritis Have Autoantibodies That React to Moesin and Demonstrate Increased Glomerular Moesin Expression

Patients with Proliferative Lupus Nephritis Have Autoantibodies That React to Moesin and Demonstrate Increased Glomerular Moesin Expression

Kidney involvement in systemic lupus erythematosus (SLE)—termed lupus nephritis (LN)—is a severe manifestation of SLE that can lead to end-stage kidney disease (ESKD). LN is characterized by immune complex deposition and inflammation in the glomerulus. We tested the hypothesis that autoantibodies ta...

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Bibliographic Details
Main Authors: Dawn J. Caster, Erik A. Korte, Michael L. Merchant, Jon B. Klein, Michelle T. Barati, Ami Joglekar, Daniel W. Wilkey, Susan Coventry, Jessica Hata, Brad H. Rovin, John B. Harley, Bahram Namjou-Khales, Kenneth R. McLeish, David W. Powell
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Journal of Clinical Medicine
Subjects:
autoantibodies
glomerulonephritis
lupus nephritis
systemic lupus erythematosus
target antigens
Online Access:https://www.mdpi.com/2077-0383/10/4/793

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