Menaquinone 4 Reduces Bone Loss in Ovariectomized Mice through Dual Regulation of Bone Remodeling

Menaquinone 4 Reduces Bone Loss in Ovariectomized Mice through Dual Regulation of Bone Remodeling

Epidemiologic studies showed that higher vitamin K (VK) consumption correlates with a reduced risk of osteoporosis, yet the dispute remains about whether VK is effective in improving bone mineral density (BMD). We sought to discover the anti-osteoporotic effect of menaquinone-4 (MK-4) and evaluate t...

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Bibliographic Details
Main Authors: Huakai Wang, Nan Zhang, Longxian Li, Pan Yang, Yongxi Ma
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Nutrients
Subjects:
menaquinone 4
ovariectomy
micro-CT
hematoxylin-eosin staining
mRNA expression
Online Access:https://www.mdpi.com/2072-6643/13/8/2570

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