HLA-G 3'UTR Polymorphisms Impact the Prognosis of Stage II-III CRC Patients in Fluoropyrimidine-Based Treatment.

HLA-G 3'UTR Polymorphisms Impact the Prognosis of Stage II-III CRC Patients in Fluoropyrimidine-Based Treatment.

An important hallmark of CRC is the evasion of immune surveillance. HLA-G is a negative regulator of host's immune response. Overexpression of HLA-G protein in primary tumour CRC tissues has already been associated to worse prognosis; however a definition of the role of immunogenetic host backg...

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Bibliographic Details
Main Authors: Marica Garziera, Ettore Bidoli, Erika Cecchin, Enrico Mini, Stefania Nobili, Sara Lonardi, Angela Buonadonna, Domenico Errante, Nicoletta Pella, Mario D'Andrea, Francesco De Marchi, Antonino De Paoli, Chiara Zanusso, Elena De Mattia, Renato Tassi, Giuseppe Toffoli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4669157?pdf=render

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http://europepmc.org/articles/PMC4669157?pdf=render

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