Comparative Hepatotoxicity of Fluconazole, Ketoconazole, Itraconazole, Terbinafine, and Griseofulvin in Rats

Oral ketoconazole was recently the subject of regulatory safety warnings because of its association with increased risk of inducing hepatic injury. However, the relative hepatotoxicity of antifungal agents has not been clearly established. The aim of this study was to compare the hepatotoxicity indu...

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Bibliographic Details
Main Authors: Star Khoza, Ishmael Moyo, Denver Ncube
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2017/6746989