Role of endoplasmic reticulum calcium signaling in the pathogenesis of Alzheimer disease

Alzheimer disease (AD) is a major threat of XXI century that is responsible for the majority of dementia in the elderly. Development of effective AD-preventing therapies are the top priority tasks for neuroscience research. Amyloid hypothesis of AD is a dominant idea in the field, but so far all...

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Bibliographic Details
Main Authors: Elena ePopugaeva, Ilya eBezprozvanny
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2013.00029/full