The role of m6A modification in the biological functions and diseases

The role of m6A modification in the biological functions and diseases

Abstract N6-methyladenosine (m6A) is the most prevalent, abundant and conserved internal cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells. m6A modification is modified by the m6A methyltransferases, or writers, such as METTL3/14/16, RBM15/15B, ZC3H3, VIRMA...

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Bibliographic Details
Main Authors: Xiulin Jiang, Baiyang Liu, Zhi Nie, Lincan Duan, Qiuxia Xiong, Zhixian Jin, Cuiping Yang, Yongbin Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-020-00450-x

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