Oxidative Stress in Hypoxic-Ischemic Encephalopathy: Molecular Mechanisms and Therapeutic Strategies

Oxidative Stress in Hypoxic-Ischemic Encephalopathy: Molecular Mechanisms and Therapeutic Strategies

Hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of morbidity and mortality in neonates. Because of high concentrations of sensitive immature cells, metal-catalyzed free radicals, non-saturated fatty acids, and low concentrations of antioxidant enzymes, the brain requires high leve...

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Bibliographic Details
Main Authors: Mingyi Zhao, Ping Zhu, Masayuki Fujino, Jian Zhuang, Huiming Guo, IdrisAhmed Sheikh, Lingling Zhao, Xiao-Kang Li
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:International Journal of Molecular Sciences
Subjects:
oxidative stress
hypoxic-ischemic encephalopathy
cell damage
therapeutic strategy
Online Access:http://www.mdpi.com/1422-0067/17/12/2078

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