"TOF2H": A precision toolbox for rapid, high density/high coverage hydrogen-deuterium exchange mass spectrometry via an LC-MALDI approach, covering the data pipeline from spectral acquisition to HDX rate analysis
<p>Abstract</p> <p>Background</p> <p>Protein-amide proton hydrogen-deuterium exchange (HDX) is used to investigate protein conformation, conformational changes and surface binding sites for other molecules. To our knowledge, software tools to automate data processing an...
Main Authors: | Koter Marek D, Chou Wayne, Pun Elroy, Nikamanon Pornpat, Gershon Paul D |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-09-01
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Series: | BMC Bioinformatics |
Online Access: | http://www.biomedcentral.com/1471-2105/9/387 |
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