Holding All the Cards—How Fanconi Anemia Proteins Deal with Replication Stress and Preserve Genomic Stability

Fanconi anemia (FA) is a hereditary chromosomal instability disorder often displaying congenital abnormalities and characterized by a predisposition to progressive bone marrow failure (BMF) and cancer. Over the last 25 years since the discovery of the first linkage of genetic mutations to FA, its mo...

Full description

Bibliographic Details
Main Authors: Arindam Datta, Robert M. Brosh
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/10/2/170