Synthesis and Anticancer Activities of Novel Guanylhydrazone and Aminoguanidine Tetrahydropyran Derivatives

In this paper we present the convenient syntheses of six new guanylhydrazone and aminoguanidine tetrahydropyran derivatives 2–7. The guanylhydrazone 2, 3 and 4 were prepared in 100% yield, starting from corresponding aromatic ketones 8a–c and aminoguanidine hydrochloride accessed by microwave irradi...

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Bibliographic Details
Main Authors: Fábio Pedrosa Lins Silva, Bruna Braga Dantas, Gláucia Veríssimo Faheina Martins, Demétrius Antônio Machado de Araújo, Mário Luiz Araújo de Almeida Vasconcellos
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/6/671