Arabica Coffee (Coffea Arabica) Fruit Skin Potential Towards the Increase of Fibroblast Cells Amount Within Socket Post Tooth Extraction of Male Wistar Mouse
Background: Tooth extraction can cause wound in hard tissue and soft tissue inside oral cavity. Wound healing process involves cell proliferation especially fibroblast cells. To accelerate fibroblast cell proliferation alternative substance that can accelerates wound healing process is needed which...
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Humanistic Network for Science and Technology
2019-06-01
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doaj-66f5d73e3d424e74b2330ac18c9dfb5c2021-02-10T03:40:59ZengHumanistic Network for Science and TechnologyHealth Notions2580-49362019-06-013626727210.33846/hn30604341Arabica Coffee (Coffea Arabica) Fruit Skin Potential Towards the Increase of Fibroblast Cells Amount Within Socket Post Tooth Extraction of Male Wistar MouseAhmad Masruri0Agus Sumono1Tecky Indriana2Dentistry Faculty, Universitas JemberBasic Dentistry Department, Dentistry Faculty, Universitas JemberBiomedic Department, Dentistry Faculty, Universitas JemberBackground: Tooth extraction can cause wound in hard tissue and soft tissue inside oral cavity. Wound healing process involves cell proliferation especially fibroblast cells. To accelerate fibroblast cell proliferation alternative substance that can accelerates wound healing process is needed which is arabica coffee fruit skin. Arabica coffee fruit skin contains substances such as polyphenols, tannin, chlorogenic acid, and caffeine expected to be able to stimulate fibroblast cells amount. Objective: To understand arabica coffee fruit skin potential towards increase in number of fibroblast cells on the socket after tooth extraction. Method: The design of this research was post test only control group with sample size of 24 wistar mouse. The samples used were divided into two groups which are control and treatment group. Then treatment was given in 3 days, 5 days, and 7 days. Then they were decapitated to undergo tissue processing with HE coloring and post tooth extraction socket fibroblast cells counting. Acquired data then analyzed used One Way ANOVA and LSD test. Result: Fibroblast cell amount increased significantly (phttp://heanoti.com/index.php/hn/article/view/357 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ahmad Masruri Agus Sumono Tecky Indriana |
spellingShingle |
Ahmad Masruri Agus Sumono Tecky Indriana Arabica Coffee (Coffea Arabica) Fruit Skin Potential Towards the Increase of Fibroblast Cells Amount Within Socket Post Tooth Extraction of Male Wistar Mouse Health Notions |
author_facet |
Ahmad Masruri Agus Sumono Tecky Indriana |
author_sort |
Ahmad Masruri |
title |
Arabica Coffee (Coffea Arabica) Fruit Skin Potential Towards the Increase of Fibroblast Cells Amount Within Socket Post Tooth Extraction of Male Wistar Mouse |
title_short |
Arabica Coffee (Coffea Arabica) Fruit Skin Potential Towards the Increase of Fibroblast Cells Amount Within Socket Post Tooth Extraction of Male Wistar Mouse |
title_full |
Arabica Coffee (Coffea Arabica) Fruit Skin Potential Towards the Increase of Fibroblast Cells Amount Within Socket Post Tooth Extraction of Male Wistar Mouse |
title_fullStr |
Arabica Coffee (Coffea Arabica) Fruit Skin Potential Towards the Increase of Fibroblast Cells Amount Within Socket Post Tooth Extraction of Male Wistar Mouse |
title_full_unstemmed |
Arabica Coffee (Coffea Arabica) Fruit Skin Potential Towards the Increase of Fibroblast Cells Amount Within Socket Post Tooth Extraction of Male Wistar Mouse |
title_sort |
arabica coffee (coffea arabica) fruit skin potential towards the increase of fibroblast cells amount within socket post tooth extraction of male wistar mouse |
publisher |
Humanistic Network for Science and Technology |
series |
Health Notions |
issn |
2580-4936 |
publishDate |
2019-06-01 |
description |
Background: Tooth extraction can cause wound in hard tissue and soft tissue inside oral cavity. Wound healing process involves cell proliferation especially fibroblast cells. To accelerate fibroblast cell proliferation alternative substance that can accelerates wound healing process is needed which is arabica coffee fruit skin. Arabica coffee fruit skin contains substances such as polyphenols, tannin, chlorogenic acid, and caffeine expected to be able to stimulate fibroblast cells amount. Objective: To understand arabica coffee fruit skin potential towards increase in number of fibroblast cells on the socket after tooth extraction. Method: The design of this research was post test only control group with sample size of 24 wistar mouse. The samples used were divided into two groups which are control and treatment group. Then treatment was given in 3 days, 5 days, and 7 days. Then they were decapitated to undergo tissue processing with HE coloring and post tooth extraction socket fibroblast cells counting. Acquired data then analyzed used One Way ANOVA and LSD test. Result: Fibroblast cell amount increased significantly (p |
url |
http://heanoti.com/index.php/hn/article/view/357 |
work_keys_str_mv |
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