Arabica Coffee (Coffea Arabica) Fruit Skin Potential Towards the Increase of Fibroblast Cells Amount Within Socket Post Tooth Extraction of Male Wistar Mouse

Background: Tooth extraction can cause wound in hard tissue and soft tissue inside oral cavity. Wound healing process involves cell proliferation especially fibroblast cells. To accelerate fibroblast cell proliferation alternative substance that can accelerates wound healing process is needed which...

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Main Authors: Ahmad Masruri, Agus Sumono, Tecky Indriana
Format: Article
Language:English
Published: Humanistic Network for Science and Technology 2019-06-01
Series:Health Notions
Online Access:http://heanoti.com/index.php/hn/article/view/357
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spelling doaj-66f5d73e3d424e74b2330ac18c9dfb5c2021-02-10T03:40:59ZengHumanistic Network for Science and TechnologyHealth Notions2580-49362019-06-013626727210.33846/hn30604341Arabica Coffee (Coffea Arabica) Fruit Skin Potential Towards the Increase of Fibroblast Cells Amount Within Socket Post Tooth Extraction of Male Wistar MouseAhmad Masruri0Agus Sumono1Tecky Indriana2Dentistry Faculty, Universitas JemberBasic Dentistry Department, Dentistry Faculty, Universitas JemberBiomedic Department, Dentistry Faculty, Universitas JemberBackground: Tooth extraction can cause wound in hard tissue and soft tissue inside oral cavity. Wound healing process involves cell proliferation especially fibroblast cells. To accelerate fibroblast cell proliferation alternative substance that can accelerates wound healing process is needed which is arabica coffee fruit skin. Arabica coffee fruit skin contains substances such as polyphenols, tannin, chlorogenic acid, and caffeine expected to be able to stimulate fibroblast cells amount. Objective: To understand arabica coffee fruit skin potential towards increase in number of fibroblast cells on the socket after tooth extraction. Method: The design of this research was post test only control group with sample size of 24 wistar mouse. The samples used were divided into two groups which are control and treatment group. Then treatment was given in 3 days, 5 days, and 7 days. Then they were decapitated to undergo tissue processing with HE coloring and post tooth extraction socket fibroblast cells counting. Acquired data then analyzed used One Way ANOVA and LSD test. Result: Fibroblast cell amount increased significantly (phttp://heanoti.com/index.php/hn/article/view/357
collection DOAJ
language English
format Article
sources DOAJ
author Ahmad Masruri
Agus Sumono
Tecky Indriana
spellingShingle Ahmad Masruri
Agus Sumono
Tecky Indriana
Arabica Coffee (Coffea Arabica) Fruit Skin Potential Towards the Increase of Fibroblast Cells Amount Within Socket Post Tooth Extraction of Male Wistar Mouse
Health Notions
author_facet Ahmad Masruri
Agus Sumono
Tecky Indriana
author_sort Ahmad Masruri
title Arabica Coffee (Coffea Arabica) Fruit Skin Potential Towards the Increase of Fibroblast Cells Amount Within Socket Post Tooth Extraction of Male Wistar Mouse
title_short Arabica Coffee (Coffea Arabica) Fruit Skin Potential Towards the Increase of Fibroblast Cells Amount Within Socket Post Tooth Extraction of Male Wistar Mouse
title_full Arabica Coffee (Coffea Arabica) Fruit Skin Potential Towards the Increase of Fibroblast Cells Amount Within Socket Post Tooth Extraction of Male Wistar Mouse
title_fullStr Arabica Coffee (Coffea Arabica) Fruit Skin Potential Towards the Increase of Fibroblast Cells Amount Within Socket Post Tooth Extraction of Male Wistar Mouse
title_full_unstemmed Arabica Coffee (Coffea Arabica) Fruit Skin Potential Towards the Increase of Fibroblast Cells Amount Within Socket Post Tooth Extraction of Male Wistar Mouse
title_sort arabica coffee (coffea arabica) fruit skin potential towards the increase of fibroblast cells amount within socket post tooth extraction of male wistar mouse
publisher Humanistic Network for Science and Technology
series Health Notions
issn 2580-4936
publishDate 2019-06-01
description Background: Tooth extraction can cause wound in hard tissue and soft tissue inside oral cavity. Wound healing process involves cell proliferation especially fibroblast cells. To accelerate fibroblast cell proliferation alternative substance that can accelerates wound healing process is needed which is arabica coffee fruit skin. Arabica coffee fruit skin contains substances such as polyphenols, tannin, chlorogenic acid, and caffeine expected to be able to stimulate fibroblast cells amount. Objective: To understand arabica coffee fruit skin potential towards increase in number of fibroblast cells on the socket after tooth extraction. Method: The design of this research was post test only control group with sample size of 24 wistar mouse. The samples used were divided into two groups which are control and treatment group. Then treatment was given in 3 days, 5 days, and 7 days. Then they were decapitated to undergo tissue processing with HE coloring and post tooth extraction socket fibroblast cells counting. Acquired data then analyzed used One Way ANOVA and LSD test. Result: Fibroblast cell amount increased significantly (p
url http://heanoti.com/index.php/hn/article/view/357
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