An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma

Haolei Tan, Yong Liu, Gangcai Zhu, Leiming Pi, Donghai Huang, Xin Zhang Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, People's Republic of China Objective: To investigate the pathology and pathogenesis of and treatment methods for...

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Main Authors: Tan HL, Liu Y, Zhu GC, Pi LM, Huang DH, Zhang X
Format: Article
Language:English
Published: Dove Medical Press 2014-09-01
Series:OncoTargets and Therapy
Online Access:http://www.dovepress.com/an-individual-drug-therapy-and-genetic-testing-report-of-temporal-bone-peer-reviewed-article-OTT
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spelling doaj-66e2a21a622d4cac8586c7477043b07d2020-11-24T23:22:17ZengDove Medical PressOncoTargets and Therapy1178-69302014-09-012014default1535154018217An individual drug-therapy and genetic testing report of temporal bone verrucous carcinomaTan HLLiu YZhu GCPi LMHuang DHZhang X Haolei Tan, Yong Liu, Gangcai Zhu, Leiming Pi, Donghai Huang, Xin Zhang Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, People's Republic of China Objective: To investigate the pathology and pathogenesis of and treatment methods for temporal bone verrucous carcinoma. Materials and methods: A single-patient report of verrucous carcinoma on the left external auditory canal is presented and analyzed along with all cases of temporal bone verrucous carcinoma that have been documented in the English literature. Results: Most of the patients with verrucous carcinoma of the temporal bone have histories of surgery, trauma, or infection, and verrucous carcinomas are sensitive to antimicrotubule chemotherapeutic medicines. Adjuvant radiation therapy is not effective, but surgical treatment might be relatively more effective. Conclusion: Temporal bone verrucous carcinoma has a poor prognosis; therefore, the preferred treatment is surgical resection facilitated with antimicrotubule chemotherapeutic treatment. Adjuvant radiation therapy is not a preferred treatment for temporal bone verrucous carcinoma. Keywords: verrucous carcinoma, temporal bone, drug therapy, genetic testinghttp://www.dovepress.com/an-individual-drug-therapy-and-genetic-testing-report-of-temporal-bone-peer-reviewed-article-OTT
collection DOAJ
language English
format Article
sources DOAJ
author Tan HL
Liu Y
Zhu GC
Pi LM
Huang DH
Zhang X
spellingShingle Tan HL
Liu Y
Zhu GC
Pi LM
Huang DH
Zhang X
An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma
OncoTargets and Therapy
author_facet Tan HL
Liu Y
Zhu GC
Pi LM
Huang DH
Zhang X
author_sort Tan HL
title An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma
title_short An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma
title_full An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma
title_fullStr An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma
title_full_unstemmed An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma
title_sort individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma
publisher Dove Medical Press
series OncoTargets and Therapy
issn 1178-6930
publishDate 2014-09-01
description Haolei Tan, Yong Liu, Gangcai Zhu, Leiming Pi, Donghai Huang, Xin Zhang Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, People's Republic of China Objective: To investigate the pathology and pathogenesis of and treatment methods for temporal bone verrucous carcinoma. Materials and methods: A single-patient report of verrucous carcinoma on the left external auditory canal is presented and analyzed along with all cases of temporal bone verrucous carcinoma that have been documented in the English literature. Results: Most of the patients with verrucous carcinoma of the temporal bone have histories of surgery, trauma, or infection, and verrucous carcinomas are sensitive to antimicrotubule chemotherapeutic medicines. Adjuvant radiation therapy is not effective, but surgical treatment might be relatively more effective. Conclusion: Temporal bone verrucous carcinoma has a poor prognosis; therefore, the preferred treatment is surgical resection facilitated with antimicrotubule chemotherapeutic treatment. Adjuvant radiation therapy is not a preferred treatment for temporal bone verrucous carcinoma. Keywords: verrucous carcinoma, temporal bone, drug therapy, genetic testing
url http://www.dovepress.com/an-individual-drug-therapy-and-genetic-testing-report-of-temporal-bone-peer-reviewed-article-OTT
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