SUATU KAJIAN MOLEKULER KETERGANTUNGAN NIKOTIN
Abstract: Nicotine, a simple chemical substance from tobacco, stimulates addiction by neuroadaptation inducing rewards system in human brain. Molecular mechanism of nicotine addiction in rewards system are mediated by nicotinic acetylcholine receptor (nAChR) and activate dopaminergic neuron. Thus, n...
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| Format: | Article |
| Language: | English |
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Universitas Sanata Dharma
2016-04-01
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| Series: | Jurnal Farmasi Sains dan Komunitas |
| Online Access: | http://e-journal.usd.ac.id/index.php/JFSK/article/view/98 |
| Summary: | Abstract: Nicotine, a simple chemical substance from tobacco, stimulates addiction by neuroadaptation inducing rewards system in human brain. Molecular mechanism of nicotine addiction in rewards system are mediated by nicotinic acetylcholine receptor (nAChR) and activate dopaminergic neuron. Thus, nicotine addiction are also induce other neurottransmitter and hormone release: norephinefrin, serotonin, opioid, glutamat and mono amine oxidase.
Keywords: nicotine, addiction, rewards system. |
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| ISSN: | 1693-5683 2527-7146 |