Biotinylated N-Acetyllactosamine- and N,N-Diacetyllactosamine-Based Oligosaccharides as Novel Ligands for Human Galectin-3
Galectin inhibitor design is an emerging research field due to the involvement of galectins in cancer. Galectin-3, in particular, plays an important role in tumor progression. To generate inhibitors, modifications of the glycan structure can be introduced. Conjugation of hydrophobic compounds to s...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-04-01
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Series: | Bioengineering |
Subjects: | |
Online Access: | http://www.mdpi.com/2306-5354/4/2/31 |