Biotinylated N-Acetyllactosamine- and N,N-Diacetyllactosamine-Based Oligosaccharides as Novel Ligands for Human Galectin-3

Galectin inhibitor design is an emerging research field due to the involvement of galectins in cancer. Galectin-3, in particular, plays an important role in tumor progression. To generate inhibitors, modifications of the glycan structure can be introduced. Conjugation of hydrophobic compounds to s...

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Bibliographic Details
Main Authors: Sophia Böcker, Lothar Elling
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:Bioengineering
Subjects:
Online Access:http://www.mdpi.com/2306-5354/4/2/31