Increased Grik4 Gene Dosage Causes Imbalanced Circuit Output and Human Disease-Related Behaviors
Summary: Altered glutamatergic neurotransmission is thought to contribute to mental disorders and neurodegenerative diseases. Copy-number variation in genes associated with glutamatergic synapses represents a source of genetic variability, possibly underlying neurological and mental disease suscepti...
Main Authors: | Vineet Arora, Valeria Pecoraro, M. Isabel Aller, Celia Román, Ana V. Paternain, Juan Lerma |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2018-06-01
|
Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718308672 |
Similar Items
-
Genetic analysis of the <it>GRIK2 </it>modifier effect in Huntington's disease
by: Myers Richard H, et al.
Published: (2006-09-01) -
Estudo de polimorfismos no gene GRIK2 em pacientes com doença de Parkinson
by: BARBOSA, Suane Reis
Published: (2018) -
Parkinson's disease and polymorphisms of the glutamatergic system genes GRIN2A, SLC1A2, and GRIK4
by: Yu. S. Mironova, et al.
Published: (2018-06-01) -
Correlation between GRIK2 rs6922753, rs2227283 polymorphism and aggressive behaviors with Bipolar Mania in the Chinese Han population
by: Haibo Ma, et al.
Published: (2019-11-01) -
GRIK3 rs490647 is a Common Genetic Variant between Personality and Subjective Well-being in Chinese Han Population
by: Lin An, et al.
Published: (2019-04-01)