β-Catenin Directs Nuclear Factor-κB p65 Output via CREB-Binding Protein/p300 in Human Airway Smooth Muscle

β-Catenin is a multifunctional protein that apart from its role in proliferative and differentiation events, also acts upon inflammatory processes, mainly via interaction with nuclear factor-κB (NF-κB). However, there is still controversy as to whether β-catenin facilitates or represses NF-κB output...

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Bibliographic Details
Main Authors: Tim Koopmans, Roos Eilers, Mark Menzen, Andrew Halayko, Reinoud Gosens
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01086/full

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