PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGIST

<p>Apixaban is a "new" oral anticoagulant, direct Xa factor inhibitor with a good evidence base of the efficacy in the prevention of ischemic stroke in patients with atrial fibrillation. The article is devoted to apixaban use in clinical practice: examination before apixaban administ...

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Main Authors: D. A. Sychev, I. I. Sinitsina, G. Yu. Zakharova, M. I. Savel'eva, A. V. Ryabova, A. V. Kryukov, A. Yu. Yurovskii
Format: Article
Language:English
Published: Stolichnaya Izdatelskaya Kompaniya 2015-09-01
Series:Racionalʹnaâ Farmakoterapiâ v Kardiologii
Subjects:
Online Access:http://www.rpcardio.ru/jour/article/view/154
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spelling doaj-66ccb771d501455f8b3489d168248d672020-11-24T21:27:54ZengStolichnaya Izdatelskaya KompaniyaRacionalʹnaâ Farmakoterapiâ v Kardiologii1819-64462225-36532015-09-0111220921610.1234/1819-6446-2015-2-209-216154PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGISTD. A. Sychev0I. I. Sinitsina1G. Yu. Zakharova2M. I. Savel'eva3A. V. Ryabova4A. V. Kryukov5A. Yu. Yurovskii6Российская медицинская академия последипломного образованияРоссийская медицинская академия последипломного образованияРоссийская медицинская академия последипломного образованияРоссийская медицинская академия последипломного образованияРоссийская медицинская академия последипломного образованияРоссийская медицинская академия последипломного образованияРоссийская медицинская академия последипломного образования<p>Apixaban is a "new" oral anticoagulant, direct Xa factor inhibitor with a good evidence base of the efficacy in the prevention of ischemic stroke in patients with atrial fibrillation. The article is devoted to apixaban use in clinical practice: examination before apixaban administration, clinical situation when laboratory control and monitoring are needed, drugs interactions (at the level of CYP3A4, P-gp), management of patients with bleeding because of apixaban therapy (including antidotes application), perioperative management of patients receiving apixaban.</p>http://www.rpcardio.ru/jour/article/view/154новые пероральные антикоагулянтыапиксабанклиническая фармакологиямежлекарственное взаимодействиекровотеченияпериоперацион-ное ведение
collection DOAJ
language English
format Article
sources DOAJ
author D. A. Sychev
I. I. Sinitsina
G. Yu. Zakharova
M. I. Savel'eva
A. V. Ryabova
A. V. Kryukov
A. Yu. Yurovskii
spellingShingle D. A. Sychev
I. I. Sinitsina
G. Yu. Zakharova
M. I. Savel'eva
A. V. Ryabova
A. V. Kryukov
A. Yu. Yurovskii
PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGIST
Racionalʹnaâ Farmakoterapiâ v Kardiologii
новые пероральные антикоагулянты
апиксабан
клиническая фармакология
межлекарственное взаимодействие
кровотечения
периоперацион-ное ведение
author_facet D. A. Sychev
I. I. Sinitsina
G. Yu. Zakharova
M. I. Savel'eva
A. V. Ryabova
A. V. Kryukov
A. Yu. Yurovskii
author_sort D. A. Sychev
title PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGIST
title_short PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGIST
title_full PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGIST
title_fullStr PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGIST
title_full_unstemmed PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGIST
title_sort practical aspects of apixaban use in clinical practice: view point of clinical pharmacologist
publisher Stolichnaya Izdatelskaya Kompaniya
series Racionalʹnaâ Farmakoterapiâ v Kardiologii
issn 1819-6446
2225-3653
publishDate 2015-09-01
description <p>Apixaban is a "new" oral anticoagulant, direct Xa factor inhibitor with a good evidence base of the efficacy in the prevention of ischemic stroke in patients with atrial fibrillation. The article is devoted to apixaban use in clinical practice: examination before apixaban administration, clinical situation when laboratory control and monitoring are needed, drugs interactions (at the level of CYP3A4, P-gp), management of patients with bleeding because of apixaban therapy (including antidotes application), perioperative management of patients receiving apixaban.</p>
topic новые пероральные антикоагулянты
апиксабан
клиническая фармакология
межлекарственное взаимодействие
кровотечения
периоперацион-ное ведение
url http://www.rpcardio.ru/jour/article/view/154
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