An interesting case of renal amyloidosis

In amyloidosis, there is an extracellular deposition of beta-sheet fibrils. Over 25 proteins have been demonstrated to form amyloid. One of them is Ig amyloid light (AL) chains. We are presenting a 40-year-old female who presented with progressive kyphoscoliosis for last 2 years following a minor tr...

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Main Authors: A Hajra, D Bandyopadhyay
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Indian Journal of Nephrology
Subjects:
Online Access:http://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2016;volume=26;issue=6;spage=467;epage=469;aulast=Hajra
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spelling doaj-66b6212f502543ecbc544ec325529c072020-11-24T21:10:41ZengWolters Kluwer Medknow PublicationsIndian Journal of Nephrology0971-40651998-36622016-01-0126646746910.4103/0971-4065.177143An interesting case of renal amyloidosisA HajraD BandyopadhyayIn amyloidosis, there is an extracellular deposition of beta-sheet fibrils. Over 25 proteins have been demonstrated to form amyloid. One of them is Ig amyloid light (AL) chains. We are presenting a 40-year-old female who presented with progressive kyphoscoliosis for last 2 years following a minor trauma and bilateral pedal edema for last 3 months. On further investigation, we found that she had a biclonal variety of MM with amyloidosis of kidney leading to massive proteinuria. Very few case reports are available where patient with biclonal variety of MM develop renal amyloidosis.http://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2016;volume=26;issue=6;spage=467;epage=469;aulast=HajraBiclonalmultiple myelomarenal amyloidosisVitamin D
collection DOAJ
language English
format Article
sources DOAJ
author A Hajra
D Bandyopadhyay
spellingShingle A Hajra
D Bandyopadhyay
An interesting case of renal amyloidosis
Indian Journal of Nephrology
Biclonal
multiple myeloma
renal amyloidosis
Vitamin D
author_facet A Hajra
D Bandyopadhyay
author_sort A Hajra
title An interesting case of renal amyloidosis
title_short An interesting case of renal amyloidosis
title_full An interesting case of renal amyloidosis
title_fullStr An interesting case of renal amyloidosis
title_full_unstemmed An interesting case of renal amyloidosis
title_sort interesting case of renal amyloidosis
publisher Wolters Kluwer Medknow Publications
series Indian Journal of Nephrology
issn 0971-4065
1998-3662
publishDate 2016-01-01
description In amyloidosis, there is an extracellular deposition of beta-sheet fibrils. Over 25 proteins have been demonstrated to form amyloid. One of them is Ig amyloid light (AL) chains. We are presenting a 40-year-old female who presented with progressive kyphoscoliosis for last 2 years following a minor trauma and bilateral pedal edema for last 3 months. On further investigation, we found that she had a biclonal variety of MM with amyloidosis of kidney leading to massive proteinuria. Very few case reports are available where patient with biclonal variety of MM develop renal amyloidosis.
topic Biclonal
multiple myeloma
renal amyloidosis
Vitamin D
url http://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2016;volume=26;issue=6;spage=467;epage=469;aulast=Hajra
work_keys_str_mv AT ahajra aninterestingcaseofrenalamyloidosis
AT dbandyopadhyay aninterestingcaseofrenalamyloidosis
AT ahajra interestingcaseofrenalamyloidosis
AT dbandyopadhyay interestingcaseofrenalamyloidosis
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