Cas9 Mediated Correction of β-catenin Mutation and Restoring the Expression of Protein Phosphorylation in Colon Cancer HCT-116 Cells Decrease Cell Proliferation in vitro and Hamper Tumor Growth in Mice in vivo

Cas9 Mediated Correction of β-catenin Mutation and Restoring the Expression of Protein Phosphorylation in Colon Cancer HCT-116 Cells Decrease Cell Proliferation in vitro and Hamper Tumor Growth in Mice in vivo

Yanlan Li,1,2,* Xiangning Li,1,3,* Jiayao Qu,1,3 Dixian Luo,1,3 Zheng Hu1,3 1Translational Medicine Institute, the First People’s Hospital of Chenzhou Affiliated to University of South China, Hunan 432000, People’s Republic of China; 2Hunan Province Key Laboratory of Tumor Cellul...

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Bibliographic Details
Main Authors: Li Y, Li X, Qu J, Luo D, Hu Z
Format: Article
Language:English
Published: Dove Medical Press 2020-01-01
Series:OncoTargets and Therapy
Subjects:
crispr/cas9
ssodn
targeted gene editing
β-catenin
colon cancer
Online Access:https://www.dovepress.com/cas9-mediated-correction-of-beta-catenin-mutation-and-restoring-the-ex-peer-reviewed-article-OTT

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https://www.dovepress.com/cas9-mediated-correction-of-beta-catenin-mutation-and-restoring-the-ex-peer-reviewed-article-OTT

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