Development of Biodegradable Nanocarriers Loaded with a Monoclonal Antibody

Development of Biodegradable Nanocarriers Loaded with a Monoclonal Antibody

Treatments utilizing monoclonal antibody therapeutics against intracellular protein-protein interactions in cancer cells have been hampered by several factors, including poor intracellular uptake and rapid lysosomal degradation. Our current work examines the feasibility of encapsulating monoclonal a...

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Bibliographic Details
Main Authors: Andrew Gdowski, Amalendu Ranjan, Anindita Mukerjee, Jamboor Vishwanatha
Format: Article
Language:English
Published: MDPI AG 2015-02-01
Series:International Journal of Molecular Sciences
Subjects:
antibody
nanoparticle
cancer
PLGA
therapy
formulation
Online Access:http://www.mdpi.com/1422-0067/16/2/3990

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