Neutral lipids associated with haemozoin mediate efficient and rapid β-haematin formation at physiological pH, temperature and ionic composition

Neutral lipids associated with haemozoin mediate efficient and rapid β-haematin formation at physiological pH, temperature and ionic composition

<p>Abstract</p> <p>Background</p> <p>The malaria parasite disposes of host-derived ferrihaem (iron(III)protoporphyrin IX, Fe(III)PPIX) by conversion to crystalline haemozoin in close association with neutral lipids. Lipids mediate synthetic haemozoin (β-haematin) format...

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Bibliographic Details
Main Authors: Ambele Melvin A, Egan Timothy J
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Malaria Journal
Subjects:
Haemozoin
β-haematin
Neutral lipids
Kinetics
Rates
Autofluorescence
Online Access:http://www.malariajournal.com/content/11/1/337

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