Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling
Synthetic biological pattern formation is challenging to engineer due to theoretical complexity and practical limitations. Here, the authors introduce a cell-in-the-loop approach in which cells interact through in silico signaling.
Main Authors: | Melinda Liu Perkins, Dirk Benzinger, Murat Arcak, Mustafa Khammash |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-15166-3 |
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