Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling

Synthetic biological pattern formation is challenging to engineer due to theoretical complexity and practical limitations. Here, the authors introduce a cell-in-the-loop approach in which cells interact through in silico signaling.

Bibliographic Details
Main Authors: Melinda Liu Perkins, Dirk Benzinger, Murat Arcak, Mustafa Khammash
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15166-3
Description
Summary:Synthetic biological pattern formation is challenging to engineer due to theoretical complexity and practical limitations. Here, the authors introduce a cell-in-the-loop approach in which cells interact through in silico signaling.
ISSN:2041-1723