Prevalence of Vitamin D Deficiency and its Correlation with Mortality in Pediatric Intensive Care Unit

• Main Authors: Mohammadreza Habibzadeh, Amin Elahi-Najafi, Amir Shafa
• Format: Article
• Language: fas
• Published: Vesnu Publications 2018-01-01
• Series: مجله دانشکده پزشکی اصفهان
• Subjects: Vitamin D deficiency; Mortality; Children; Pediatric intensive care units
• Online Access: http://jims.mui.ac.ir/index.php/jims/article/view/8743

Background: Vitamin D deficiency is common in pediatric intensive care unit (PICU) and is related with mortality. The aim of current study was evaluation of prevalence and correlation between vitamin D deficiency and mortality in pediatric intensive care unit. Methods: In this cross-sectional study, 61 pediatrics patients admitted to pediatric intensive care unit were enrolled according to inclusion and exclusion criteria. Serum levels of vitamin D were measured in the patients at onset of study; then, patients were allocated into two groups of vitamin D deficiency (less than 20 ng/ml) and normal (vitamin D of more than 20 ng/ml). Mortality rate was evaluated in patients according to pediatric risk of mortality III (PRISM III) and pediatric index of mortality 2 (PIM 2). Findings: Both the indexes (PIM 2 and PRISM III) were higher in vitamin D deficiency group (P = 0.020 and P < 0.0001, respectively). There was no significant correlation between serum level of vitamin D with PIM 2 (P = 0.590) and PRISM III (P = 0.180). Conclusion: According to our results, the prevalence of mortality was higher in vitamin D deficiency group compared to normal group; but there was no significant correlation between serum levels of vitamin D and mortality rate.