Transcriptomics-Based Repositioning of Natural Compound, Eudesmin, as a PRC2 Modulator

Transcriptomics-Based Repositioning of Natural Compound, Eudesmin, as a PRC2 Modulator

Extensive epigenetic remodeling occurs during the cell fate determination of stem cells. Previously, we discovered that eudesmin regulates lineage commitment of mesenchymal stem cells through the inhibition of signaling molecules. However, the epigenetic modulations upon eudesmin treatment in genome...

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Bibliographic Details
Main Authors: Sang Ah Yi, Ki Hong Nam, Min Gyu Lee, Hwamok Oh, Jae Sung Noh, Jae Kyun Jeong, Sangwoo Kwak, Ye Ji Jeon, So Hee Kwon, Jaecheol Lee, Jeung-Whan Han
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
eudesmin
transcriptome
polycomb repressive complex 2
wnt
pluripotency
Online Access:https://www.mdpi.com/1420-3049/26/18/5665

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