Clinical observation of diabetic retinopathy after transplantation of autologous stem cell in diabetic patients

AIM: To observe the effect of autologous stem cell transplantation in diabetic retinopathy.<p>METHODS:Totally 58 cases(116 eyes)who underwent autologous stem cell transplantation were confirmed as no diabetic retinopathy(18 eyes), mild non-proliferative diabetic retinopathy(NPDR)(41 eyes), mid...

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Bibliographic Details
Main Authors: Xiao-Lin Hao, Xiu-Ling Ye, Zhong-Chen Zhang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2014-09-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://www.ies.net.cn/cn_publish/2014/9/201409045.pdf
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Summary:AIM: To observe the effect of autologous stem cell transplantation in diabetic retinopathy.<p>METHODS:Totally 58 cases(116 eyes)who underwent autologous stem cell transplantation were confirmed as no diabetic retinopathy(18 eyes), mild non-proliferative diabetic retinopathy(NPDR)(41 eyes), mid-level NPDR(51 eyes); severe NPDR(6 eyes)by ophthalmoscope directly or indirectly and fluorescence fundus angiography(FFA). Follow-up was 6-12mo, the changes of retinopathy were observed. <p>RESULTS:The total effective rate of vision and retinopathy was 84.4%, 76.7%. The results of severe NPDR was statistically worse than the other groups(<i>P</i>< 0.05).<p>CONCLUSION:The stable blood glucose level and improved pancreatic function after autologous stem cell transplantation might be helpful in diabetic retinopathy, the long effects need to be researched further.
ISSN:1672-5123
1672-5123