Short-Term Calorie Restriction Maintains Plasma Insulin Concentrations along with a Reduction in Hepatic Insulin-Degrading Enzyme Levels in db/db Mice

Short-Term Calorie Restriction Maintains Plasma Insulin Concentrations along with a Reduction in Hepatic Insulin-Degrading Enzyme Levels in db/db Mice

Maintaining blood insulin levels is important for patients with diabetes because insulin secretion capacity declines with the development of the disease. Calorie restriction (CR) is effective for the improvement of glucose tolerance, but it is not clear whether CR can maintain insulin levels in the...

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Bibliographic Details
Main Authors: Yudai Nonaka, Reo Takeda, Yutaka Kano, Daisuke Hoshino
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Nutrients
Subjects:
calorie restriction
glucose transporter 4 (GLUT-4)
insulin-degrading enzyme (IDE)
diabetes
Online Access:https://www.mdpi.com/2072-6643/13/4/1190

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