Extracellular matrix and its therapeutic potential for cancer treatment

Abstract The extracellular matrix (ECM) is one of the major components of tumors that plays multiple crucial roles, including mechanical support, modulation of the microenvironment, and a source of signaling molecules. The quantity and cross-linking status of ECM components are major factors determi...

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Bibliographic Details
Main Authors: Jiacheng Huang, Lele Zhang, Dalong Wan, Lin Zhou, Shusen Zheng, Shengzhang Lin, Yiting Qiao
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00544-0