Swainsonine, an alpha-mannosidase inhibitor, may worsen cervical cancer progression through the increase in myeloid derived suppressor cells population.

Swainsonine, an alpha-mannosidase inhibitor, may worsen cervical cancer progression through the increase in myeloid derived suppressor cells population.

Cervical cancer, caused by high oncogenic risk Human Papillomavirus (HPV) infection, continues to be a public health problem, mainly in developing countries. Using peptide phage display as a tool to identify potential molecular targets in HPV associated tumors, we identified α-mannosidase, among oth...

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Bibliographic Details
Main Authors: Caio Raony Farina Silveira, Marcella Cipelli, Carolina Manzine, Silvia Helena Rabelo-Santos, Luiz Carlos Zeferino, Gretel Rodríguez Rodríguez, Josiane Betim de Assis, Suellen Hebster, Isabel Bernadinelli, Fabio Laginha, Enrique Boccardo, Luisa Lina Villa, Lara Termini, Ana Paula Lepique
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213184

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