Ensuring the Stability of the Genome: DNA Damage Checkpoints

The cellular response to DNA damage is vital for the cell�s ability to maintain genomic integrity. Checkpoint signalling pathways, which induce a cell cycle arrest in response to DNA damage, are an essential component of this process. This is reflected by the functional conservation of these pathway...

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Bibliographic Details
Main Authors: Christine Latif, Susan H. Harvey, Susan J. O'Connell
Format: Article
Language:English
Published: Hindawi Limited 2001-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2001.297